Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses IZI-BB
Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses IZI-BB

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Research & Development

At Fraunhofer IZI-BB we develop analytical and biotechnological solutions for medical problems, animal health, nutrition, cosmetics and the environment. Our research focuses on sample preparation, development of molecular recognition elements and data acquisition as well as miniaturization and automation of corresponding technologies in order to provide reliable, flexible and easy-to-use process flows for our customers. In addition, a major focus of the institute is the production of functional proteins by means of cell-free protein synthesis as well as the development of methods for obtaining, handling and manipulating cells and biomolecules.

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Microarray Technologies

The activity profile essentially comprises the application of defined quantities (spotting) of biological sample material to a predefined surface. The range of (biological) samples processed extends from nucleic acids (DNA, RNA and aptamers), peptides and proteins to complex samples such as serum, cell extract and vital cells.

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With the available equipment the physico-chemical properties of the samples can be taken into account and under identical conditions the samples can be dispensed very gently. Modified slides as well as membranes, wafers and pre-structured 3-dimensonal objects for ivD and lab-on-a-chip applications in different sizes can be used as targets for the samples. The offer is rounded off by the possibility of specific structuring and modification of surfaces and their characterization.