Assay and Biosensor Development

The entire process of molecular bioanalysis as well as large areas of chemical and process analytics are mapped at Fraunhofer IZI-BB. This includes the development of a workflow from sample handling of the smallest quantities to analysis using biosensors or biochips. Substances analysed include the entire range of biologically relevant molecules, such as DNA oligomers, PCR products, cells, aptamers, RNA, peptides, antibodies and other proteins, as well as all types of »small molecules« used as potential active substances, e.g. in screening.

 

We offer expertise starting with the question of the object to be analyzed, through the selection of suitable methods, sample preparation and the measurement itself, to data acquisition and evaluation. On request, we also interpret the results and provide support for their utilization.

 

Biosensor Technology

Flexible technology platform

also for parallel multiparameter analyses

 

Microarrays

Spot customer-specific DNA,

peptide, protein and cell microarrays

 

Biomarker Validation

Development of assays for the validation of biomarkers - adaptation to different platforms

 

Functional Nucleic Acids - Aptamers

Synthesis and functionalization of aptamers - Aptasensors for analytical and therapeutic applications

 

Binders for Biomolecules

From small compounds to proteins

 

Haemocompatibility

Blood compatibility of cardiovascular medical devices

 

Homogeneous Immunoassays

Rapid mix-and-measure tests without washing steps

 

Smart Dry Reagents

Freeze-drying of immunoassay reagents